Recent Publications:
Funkelstein L, Beinfeld M, Minokadeh A, Zadina J, Hook V. (2010)
Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides.
Neuropeptides 44, 457-66.
Hook V, Bark S, Gupta N, Lortie M, Lu WD, Bandeira N, Funkelstein L, Wegrzyn J, O'Connor DT, Pevzner P. (2010)
Neuropeptidomic components generated by proteomic functions in secretory vesicles for cell-cell communication.
AAPS J. 12, 635-45.
Gupta N, Bark SJ, Lu WD, Taupenot L, O'Connor DT, Pevzner P, Hook V. (2010)
Mass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processing.
J Proteome Res. 9, 5065-75.
(more)
Highlighted Publications:
Hook, V., Funkelstein, L., Lu, D., Bark, S., Wegrzyn, J., and Hwang, S.R. (2008)
Proteases for processing proneuropeptides into peptide neurotransmitters and hormones.
Annu. Rev. Pharmacol. Tox. 48, 393-423.
Hwang, S-R., Garza, C., Mosier, C., Toneff, T., Wunderlich, E., Goldsmith, P., and Hook, V. (2007)
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion.
J. Biol. Chem. 282, 9556-9563.
(more)