University of California, San Diego | Skaggs School of Pharmacy and Pharmaceutical Sciences

GRADUATE STUDIES

Dr. Vivian Hook, Faculty Member of Graduate Programs at UC San Diego:

Neurosciences Graduate Program
Biomedical Sciences Graduate Program
Bioinformatics Graduate Program


Training Program in ‘Neuroscience Related to Drug Abuse.’
It is important to implement research training for future scientists in modern aging research. The increased incidence of disease in the aged population demonstrates the need for training of future scientists to develop new drug targets and drug molecules for the treatment of disease. Dr. Vivian Hook is Director of the NIH-funded training program in ‘Neuroscience Related to Drug Action’, for predoctoral and doctoral trainees at the Univ. of Calif., San Diego. The goal of the training program is to allows trainees to gain state-of-the-art expertise in modern post-genomic approaches in defining the molecular bases for regulation of cellular functions in the nervous system. The understanding of how to approach basic research with the goal of finding the key regulatory of the biological system as a potential drug target will allow young investigators to apply basic research findings to drug development.

Mentoring of Young Scientists for Predoctoral, Postdoctoral, and Scientist Trainee Fellowships.
Vivian Hook has providing successful advising of research design and proposal planning for individual fellowship awards for graduate students, postdoctoral scholars, and mentored scientists. These awards to trainees are mentored by Dr. V. Hook to promote the scientific research careers of new investigators.

Research Training in Pharmaceutical Sciences for Pharmacy and Medical Students.
Research training internships for pharmacy and medical students at UC San Diego provide health professional students with medical therapeutic oriented investigation of disease mechanisms that provide insight into new pharmaceutical drug discovery strategies.

Summer Undergraduate Research Internships
Several summer internships for undergraduate students provide training in experimental design for answering key scientific questions.

Applications for Research Training
Please prepare a CV and a one-page statement of research interest. Apply online

 

Recent Publications:

Funkelstein L, Beinfeld M, Minokadeh A, Zadina J, Hook V. (2010) Unique biological function of cathepsin L in secretory vesicles for biosynthesis of neuropeptides. Neuropeptides 44, 457-66.

 

Hook V, Bark S, Gupta N, Lortie M, Lu WD, Bandeira N, Funkelstein L, Wegrzyn J, O'Connor DT, Pevzner P. (2010) Neuropeptidomic components generated by proteomic functions in secretory vesicles for cell-cell communication. AAPS J. 12, 635-45.

 

Gupta N, Bark SJ, Lu WD, Taupenot L, O'Connor DT, Pevzner P, Hook V. (2010) Mass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processing. J Proteome Res. 9, 5065-75.

 

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Highlighted Publications:

Hook, V., Funkelstein, L., Lu, D., Bark, S., Wegrzyn, J., and Hwang, S.R. (2008) Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu. Rev. Pharmacol. Tox. 48, 393-423.

 

Hwang, S-R., Garza, C., Mosier, C., Toneff, T., Wunderlich, E., Goldsmith, P., and Hook, V. (2007) Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion. J. Biol. Chem. 282, 9556-9563.


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