University of California, San Diego | Skaggs School of Pharmacy and Pharmaceutical Sciences
CONTACT
Dr. Vivian Hook
Principal Investigator
Mailing Address:
9500 Gilman Drive #0744
La Jolla, CA 92093-0744
Telephone: 858-822-6682
Fax: 858-822-6681
E-mail: vhook@ucsd.edu
Jill Wegrzyn
Webmaster
Mailing Address:
9500 Gilman Drive #0744
La Jolla, CA 92093-0744
Telephone: 858-822-6695
Fax: 858-822-6696
E-mail: jwegrzyn@ucsd.edu
Members
| Shin-Rong Hwang | Molecular Biology/Biochem | srhwang@ucsd.edu | 822-6684 |
| Steven Bark | Mass Spectrometry/Proteomics | sbark@ucsd.edu | 822-6685 |
| Lydiane Funkelstein | Neurobiology | lfunkelstein@ucsd.edu | 822-6684 |
| Doug Lu | Biophysics/Biochem | wdlu@ucsd.edu | 822-6685 |
| Thomas Toneff | Neurochemistry | ttoneff@ucsd.edu | 822-6684 |
| Jill Wegrzyn | Bioinformatics | jwegrzyn@ucsd.edu | 822-6695 |
| Charles Mosier | Neurochemistry | cmosier@ucsd.edu | 822-6684 |
| Ardalan Minokadeh | Neurosciences | arminoka@ucsd.edu | 822-6685 |
| Gloria Sanchez | School of Pharmacy | glsanchez@ucsd.edu | 822-6684 |
| Graduate Student Research Rotations - Summer Research Internships | |||
| Undergraduate Research, Independent Study | |||
| Visiting Students and Scientists | |||
Publications In Press:
Hook, V., Funkelstein, L., Lu, D., Bark, S., Wegrzyn, J., and Hwang, S.-R. (2007) Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu. Rev. Pharmacol. Tox.
Bark, S.J., and Hook, V. (2007) Differentical recovery of peptides from sample tubes and the reproducibility of quantitative proteomic data. J. Proteome Research.
Publications:
Hook, G., Hook, V.Y.H., and Kindy, M. (2007) Cysteine protease inhibitors reduce brain beta-amyloid and beta-secrease activity in vivo and are potential Alzheimer's disease therapeutics. Biol. Chem. 388, 979-983.
Hwang, S.R., and Hook, V.Y.H. (2007) Multiple domains of endopin 2A for serpin cross-class inhibition of papain. Arch. Biochem. Biophys. 46, 219-224.