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External Resources:

Dr. Joseph D. Ma

Clinical Pharmacology

Joseph D. Ma

Joseph D. Ma, Pharm.D.

Professor of Clinical Pharmacy
Skaggs School of Pharmacy and Pharmaceutical Sciences

Email
joema@ucsd.edu

Phone
(858) 822-3485


Research Summary: Clinical Pharmacology and Pain Management

Dr. Ma’s research interests are in examining methods that evaluate drug-drug interactions. His research has elucidated that several methods estimating in vivo, real-time, drug-metabolizing enzyme activity are inadequate and lack optimal validation. Dr. Ma is also interested in examining pain medication pharmacokinetic and pharmacodynamic variability in opioid-treated, cancer patients. 

Dr. Ma's clinical practice is in pain and palliative care in an outpatient, multidisciplinary clinic at the Moores Cancer Center. Under a collaborative practice protocol, Dr. Ma sees patients and is able to start, stop, or modify therapy to treat symptoms and sides effects of a disease and its treatment. 

Academic Achievements

Education:

B.S. Biology, UC Irvine (1998); Pharm.D., UC San Francisco (2002); Fellowship Clinical Pharmacology/Drug Metabolism, Bassett Healthcare, Cooperstown, NY (2002-2004). Excellence in Achievement, American College of Clinical Pharmacology (2016).

Awards and Honors:

NIDA Intramural Research Training Award, NIH (1997, 1998); UCSD SSPPS Faculty Teaching Award (2008, 2013); Fellow Clinical Pharmacology (2015)

Leadership Experience:

Clinical Trial Associate, Early Development, Amgen, Inc. (2004-2007); Meeting Program Committee Member, ACCP Annual Meeting, San Antonio, TX, (2009); Co-chair, Symposium: Innovations and Controversies in Quantifying Drug-Drug Interactions, ACCP Annual Meeting, San Antonio, TX, (2009), Meeting Program Co-chair, ACCP Annual Meeting, San Diego, CA (2012). 

Teaching

  • Pharmacogenomics (SPPS219/PHARM235)
  • Pharmacy Therapeutics (SPPS 212B)
  • Drug Discovery, Development, & Commercialization (SPPS273/BIOM267 /PHARM210/MGT217250)

Key Contributions to Pharmaceutical Sciences

  • Evaluated accuracy and validity of in vivo cytochrome P450 (CYP) and P-glycoprotein phenotyping methods and probe drugs.
  • Established novel course elective for pharmacy, medical, law, graduate, and business students encompassing areas of drug discovery, development, and commercialization.
  • Clinical research in in vivo phenotyping studies, methodology evaluation, and utility of limited sampling strategies.

Selected Recent Publications (view more)

Potential Collaborative Programs with the Pharmaceutical Industry

  • Experience in private and public sector in clinical
    trial operations, management, and execution.
  • Experience in Proof of concept, phase I (FIH), and drug-drug interaction studies.
  • Developing novel teaching methods for health care professionals encompassing areas of drug discovery, development, and commercialization.