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Dr. Linda Awdishu

Kidney Diseases

Linda Awdishu

Linda Awdishu, Pharm.D., MAS

Health Sciences Associate Clinical Professor of Pharmacy
Skaggs School of Pharmacy and Pharmaceutical Sciences

Email
lawdishu@ucsd.edu

Phone
(858) 534-3919


Research Summary: Kidney Diseases

Dr. Awdishu’s research program involves pharmacokinetics of drugs and dosing in kidney disease. Currently, Dr. Awdishu is co-directing The International Drug Induced Renal Injury Consortium (DIRECT) in collaboration with The International Serious Adverse Event Consortium (iSAEC).

DIRECT will investigate the genetic basis of serious drug induced renal injury, through a collaborative network comprised of leading clinical research centers from around the world.

Academic Achievements

Education:B.S. in Pharmacy (1999) University of Toronto; Pharm.D. (2008) University of Colorado; Masters of Advanced Studies in Clinical Research (2007) University of California, San Diego.

Awards and Honors: : Award for Excellence in Medication Use Safety, American Society of Health Systems Pharmacists Foundation (2014); Barbara and Paul Saltman Distinguished Teaching Award, UC San Diego Academic Senate (2015); Teacher of the Year, UCSD School of Pharmacy (2012); Apples for Preceptors Award, UCSF School of Pharmacy (2008); Preceptor of the Year Award, UCSD Pharmacy Practice Residency Program (2007); San Diego Preceptor of the Year Award, UCSF School of Pharmacy (2006); Canadian Society of Hospital Pharmacy National Schering Award for Pharmacokinetics (2003); Canadian Society of Hospital Pharmacy, Ontario Branch Douglas J Stewart Award for Hospital Administrators (2002).

Leadership Experience: Director of Interprofessional Education and Simulation, Manager of UC San Diego Health Systems Chronic Kidney Disease Program.

Teaching

  • Pharmacy: Therapeutics (SPPS 212A), APPE (Ambulatory Care Chronic Kidney Disease and Solid Organ Transplant), Pharmacy residency rotations in ambulatory care, Objective Structured Clinical Experiences, Inter-professional Education Experiences
  • Medicine: Interprofessional Education experiences and research mentor.
  • Masters for Advanced Studies in Clinical Research: Faculty Mentor, Research Mentor

Key Contributions to Pharmaceutical Sciences

  • Developed institutional Pharmacy and Therapeutics Protocols for Prescribing in Renal Disease as well as electronic algorithms for renal dosage adjustments.
  • Implemented electronic GFR reporting at the clinical laboratories for UCSD Medical Center.
  • Developed and leads a multidisciplinary Chronic Kidney Disease Program at UC San Diego Health System. http://health.ucsd.edu/specialties/nephrology/Pages/chronic-kidney-disease.aspx
  • Project leader for the development of patient education videos for the Chronic Kidney Disease Program: https://www.youtube.com/channel/UCOaegTYfii7Gl9ytqZa8i_Q
  • Developed clinical pharmacy transplant services at UCSD Medical Center.
  • Clinical research in chronic kidney disease and acute kidney injury in the ambulatory and hospitalized patient populations.

Selected Recent Publications (view more)

Yeung et al. (2004). Pharmacokinetics of Oral Ciprofloxacin in Non-Infected Patients on Continuous Cycling Peritoneal Dialysis. Peritoneal Dialysis International 24:447-453.

Steiner et al. (2011). Steroids in Kidney Transplant Patients. Semin Immunopathol. 33:157-67.

Awdishu et al. (2007). Drug Issues in Renal ReplacementTherapies. In: Dunsworth T, Richardson M, Cheng J, et al, eds. Pharmacotherapy Self Assessment Program, 6th ed. Nephrology. Lenexa, KS: American College of Clinical Pharmacy 91-105.

Steiner et al. (2011). Steroids in Kidney Transplant Patients. Semin Immunopathol. 33:157-67.

Awdishu et al. (2011). How to optimize drug delivery in renal replacement therapy. Semin Dial. 24:176-82.

Verma M. et al. (2014). Impact of single immunosuppressive drug withdrawal on lymphocyte immunoreactivity. J Surg Research. 188:309-315.

Mehta et al. (2015) Phenotype standardization for drug induced kidney disease. http://www.ncbi.nlm.nih.gov/pubmed/25853333

RamachandranRao et al. (2015) Proteomic analysis of urine exosomes reveals renal tubule response to leptospiral colonization in experimentally infected rats. http://www.ncbi.nlm.nih.gov/pubmed/25793258

Awdishu L et al. (2016) Role of pharmacogenomics in kidney disease and injury. Adv Chronic Kidney Dis. Mar;23(2):106-19. https://www.ncbi.nlm.nih.gov/pubmed/26979149

Awdishu L et al. (2016) Impact of real time alerting on appropriate prescribing in kidney disease.: a cluster randomized controlled trial. J Am Med Inform Assoc. May;23(3):609-16. https://www.ncbi.nlm.nih.gov/pubmed/26615182

Atayee RS et al. (2016) Using Simulation to Improve First-Year Pharmacy Students' Ability to Identify Medication Errors Involving the Top 100 Prescription Medications. Am J Pharm Educ. Jun 25;80(5):86. https://www.ncbi.nlm.nih.gov/pubmed/27402989

Potential Collaborative Programs with the Pharmaceutical Industry

  • Pharmacogenomic studies of drug induced nephrotoxicity.
  • Pharmacokinetic studies in kidney disease and transplantation.