The Skaggs School of Pharmacy & Pharmaceutical Sciences

Jennifer Le

Dr. Jennifer Le is an Assistant Professor of Clinical Pharmacy at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS). She is also an Assistant Clinical Professor of Pharmacy, non-salaried for the University of California, San Francisco (UCSF) School of Pharmacy. She received a Bachelor of Science degree from the University of California, Los Angeles in 1995, and her Doctorate degree in Pharmacy from UCSF in 2000. After completing a pharmacy practice residency at Long Beach Memorial Medical Center & Miller Children's Hospital in 2001, Dr. Le initiated her career in academia. After seven years at Western University of Health Sciences, College of Pharmacy, she joined UCSD in June 2009 to focus on further developing her research program.

Dr. Le co-chairs and lectures in the Therapeutics series, including courses in applied pharmacokinetics such as therapeutic drug monitoring and special populations. She provides clinical rotations in medicine to fourth-year pharmacy students. She also mentors students and residents research projects. As a board certified pharmacotherapy specialist with added qualification in infectious diseases, Dr. Le maintains a clinical practice site at Long Beach Memorial Medical Center and Miller Children's Hospital where she conducts most of her patient-oriented research.

Dr. Le received an Investigator Development Award in 2007-8 from the American College of Clinical Pharmacy for her study on translational research in hospitalized patients with serious infections caused by resistant Gram-negative bacteria. She has published over 12 peer-reviewed journal articles (most as first author), and presented over 14 abstracts at scientific meetings related to her research program.

Research Interest

Dr. Jennifer Le's primary research interests encompass the safe use of antimicrobial agents, their pharmacokinetic and pharmacodynamic properties, and outcomes associated with resistant infections in neonatal and pediatric populations. She has published some original research studies within these areas.

Selected Publications

Elstner E, Linker-Israeli M, Umiel T, Le J, et al. Combination of a potent 20-epi-vitamin D3 analogue (KH1060) with 9-cis-retinoic acid irreversibly inhibits clonal growth, decreased bcl-2 expression, and induces apoptosis in HL-60 leukemic cells. Cancer Research. 1996;56:3570-3576.

Asou H, Koike M, Elstner E, Cambell M, Le J, et al. 19-nor vitamin D analogs: a new class of potent inhibitors of proliferation and inducers of differentiation of human myeloid leukemia cell lines. Blood. 1998;92:2441-9.

Le J, Tsourounis C. Implanon: a critical review. Annals of Pharmacotherapy 2001:35:329-336.

Le J, Lipsky M. Management of bacterial rhinosinusitis. American Journal of Managed Care 2004;4:S3-11.

Le J, Briggs G, McKeown A, Bustillo J. Urinary tract infections during pregnancy. Annals of Pharmacotherapy 2004;38:1692-1701.

Le J, Lipsky M. Therapeutic management of bronchitis. American Journal of Managed Care 2005;5:S3-10.

Le J, Nguyen T, Law A, Hodding J. Adverse drug reactions in pediatrics over a 10-year period. Pediatrics 2006;118:555-562.

Le J, Lieberman JM. Management of community-associated methicillin-resistant Staphylococcus aureus infections in children. Pharmacotherapy 2006;26:1758-1770.

Le J, Nguyen T, Okamoto M, Lieberman JM. Impact of empiric antibiotic use on the development of infections caused by extended-spectrum beta-lactamase bacterial pathogens in the neonatal intensive care unit. Pediatric Infectious Diseases Journal 2008;27:314-318.

Le J, Adler-Shohet FC, Nguyen C, Lieberman JM. Nephrotoxicity associated with conventional amphotericin B in neonates. Pediatric Infectious Diseases Journal (tentative publication date 12/2009).

List of Publications in Pub Med