Tadeusz (Ted) Franciszek Molinski

Molinski

Ph.D. 1985, Research School of Chemistry,
Australian National University

Dr. Ted Molinski is a Professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences. He received his B.S. in Chemistry from Monash University, Melbourne, in 1979, and his Ph.D. from Australian National University in 1984. Dr. Molinski was a Postdoctoral Fellow at UC San Diego from 1984-87.

Key Words: Marine Alkaloids, Lyngbya confervoides, Phorbasterones A-D, marine natural products, Pharmacognosy, Marine Natural Products, Organic Synthesis, Anticancer, Antifungal Agents

Research Interests: Bioorganic chemistry, marine natural products, NMR and structure elucidation, structure-activity, synthesis. Marine invertebrates produce organic compounds with profound biological activity. Our research focuses on the chemistry, bioorganic chemistry of marine natural products with novel structural and biological properties

Selected Publications:

Molinski, T.F.; Makarieva, T.N.; Stonik, V.A. (–)-Rhizochalin is a Dimeric Enantiomorphic (2R)-Sphingolipid. Analysis of pseudo-C2v Symmetric bis-2-Amino-3- Alkanols by CD” Angew. Chem., Intl. Ed. 2000, 39(22), 4076-4079.

Franz, A.H.; Molinski, T.F.; Lebrilla, C.B. “MALDI-FTMS Characterization of Oligosaccharides Labeled with 9-Aminofluorene” J. Am. Soc. Mass Spec. 2001, 12(12), 1254-1261.

Zhou, G-X.; Molinski, T.F. “Long-Chain Acetylenic Ketones from the Micronesian Sponge Haliclona sp. Importance of the 1-yn-3-ol Group for Antitumor Activity” Mar. Drugs 2003, 1(1), 46-53.

Richter, R.K.; Mickus, D.E.; Rychnovsky, S.D.; Molinski, T.F. “Differential Modulation of the Antifungal Activity of Amphotericin B by Natural and ent-Cholesterol” Bioorg. Med. Chem. Lett. 2004, 14(1), 115-118.

Masuno, M.N.; Pawlik, J.R. Molinski, T.F. “Phorbasterones A-D. Cytotoxic Nor-Ring A Steroids from the Sponge Phorbas amaranthus” J. Nat. Prod. 2004, 67(4), 731-733.

Molinski, T.F. “Antifungal Compounds from Marine Organisms.” Curr. Med. Chem.: Anti-Infect. Agents 2004, 3(3), 197-220.

Andersen, R.J.; Ireland, C.M.; Molinski, T.F.; Bewley, C.B.“D. John Faulkner: ASP Research Achievement Award” J. Nat. Prod. 2004, 67(8), 1239-1251.

MacMillan, J.B.; Molinski, T.F. “Long-Range Stereo-Relay. Relative and Absolute Configuration of 1,n-Glycols from Circular Dichroism of Liposomal Porphyrin Esters J. Am. Chem. Soc. 2004, 126(32), 9944-9945

List of Publications in Pub Med