Webb DR, Handel TM, Kretz-Rommel A, Stevens RC. (2013) Opportunities for functional selectivity of GPCR antibodies. Biochem Pharmacol. 85:147-52.

Axelsson J, Xu D, Na Kang B, Nussbacher JK, Handel TM, Ley K, Sriramarao P, Esko JD. (2012) Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood. 120:1742-51.

O'Hayre M, Niederst M., Fecteau J.F., Nguyen V.M., Kipps T.J., Messmer D., Newton A.C., Handel T.M. (2012) Mechanisms and Consequences of the Loss of PHLPP1 Phosphatase in Chronic Lymphocytic Leukemia (CLL). Leukemia. 26:1689-92.

Zhang S, Condac E., Qiu H., Jiang J., Gutierrez-Sanchez G., Bergmann C., Handel T., Wang L. (2011) Heparin-Induced Leukocytosis Requires 6-O-Sulfation and is Caused by Blockade of Selectin- and CXCL12-Mediated Leukocyte Trafficking in Mice. J Biol Chem. 287:5542-53..

Fecteau J.F., Bharati I.S., O'hayre M, Handel T.M., Kipps T.J., Messmer D. (2011) Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and Mcl-1. Mol Med. 18:19-28

X. Wang, C. Watson, J.S. Sharp, T.M. Handel and J.H. Prestegard. (2011) Oligomeric structure of the chemokine RANTES/CCL5 from NMR, MS and SAXS data. Structure. 19:1138-48.

Kulig P, Kantyka T, Zabel BA, Banas M, Chyra A, Stefanska A, Tu H, Allen SJ, Handel TM, Kozik A, Potempa J, Butcher EC, Cichy J. Immunol. 2011 187:1403-10.

S.J. Allen, D.J. Hamdel and T.M. Handel. (2011) A Rapid and efficient way to obtain modified chemokinesfor functional and biophysical studies. Cytokine. 55:168-73.

E. Laborde, R.W. Macsata, F. Meng, B.T. Peterson, L. Robinson, S.R. Schow, R.J. Simon, H. Xu, K. Baba, H. Inagaki, Y. Ishiwata, T. Jomori, Y. Matsumoto, A. Miyachi, T. Nakamura, M. Okamoto, T.M. Handel, C.C. Bernard. (2011) Discovery, Optimization, and Pharmacological Characterization of Novel Heteroaroylphenylureas Antagonists of C-C Chemokine Ligand 2 Function. J Med Chem 54:1667-81.

M.S. Hanes, K.A. Reynolds, C. McNamara, P. Ghosh, R.A. Bonomo, J.F. Kirsch and T.M. Handel. (2011) Specificity and cooperativity at b-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins 79:1267-76.

C.L. Salanga and T.M. Handel. (2011) Chemokine Oligomerization and Interactions with Receptors and Glycosaminoglycans: The Role of Structural Dynamics in Function. Experimental Cell Research 317:590-601.

X. Yin, J. Truty, R. Lawrence, S.C. Johns, R.S. Srinivasan, T.M. Handel, M.M. Fuster. (2010) A critical role for lymphatic endothelial heparan sulfate in lymph node metastasis. Mol Cancer. 9:316.

M. O'Hayre, C.L. Salanga, T.M. Handel, D.J. Hamel (2010) Emerging Concepts and Approaches for Chemokine-Receptor Drug Discovery. Expert Opinion in Drug Discovery. 5:1109-1212.

D. Messmer, J.F. Fecteau, M. O’Hayre, I,S. Bharati, T.M. Handel, and T.J. Kipps (2010) Chronic Lymphocytic Leukemia Cells Receive Raf-dependent Survival Signals In Response To CXCL12 That Are Sensitive To Inhibition By Sorafenib. Blood 17:882-9.

B. Wu, E.Y.T. Chien, C.D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D.J. Hamel, P. Kuhn, T.M. Handel, V. Cherezov, R.C. Stevens (2010) Structures of the CXCR4 chemokine receptor in complex with small molecule and cyclic peptide antagonists. Science 330:1066-1071.

A.E.I. Proudfoot, I. Severin, D. Hamel, and T.M. Handel. Structural Aspects of Chemokines, GAGS and their Interactions in: "CHEMOKINE RECEPTORS AS DRUG TARGETS". Editors: Rob Leurs, Martine Smit, and Sergio Lira. In Press.

Hanes MS, Ratcliff K, Marqusee S, Handel TM. (2010) Protein-protein binding affinities by pulse proteolysis: Application to TEM-1/BLIP protein complexes. Protein Sci. Epub ahead of Print

M. O'Hayre, C.L. Salanga, T.J. Kipps, D. Messmer, P.C. Dorrestein, T.M. Handel (2010) Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomic Analysis. PLoS One. 5:e11716. PMCID: PMC2908618

Handel T.M, Horuk R. (2010) Duffy antigen inhibitors: useful therapeutics for malaria? Trends Parasitol. 2010 26:329-33.

I.C. Severin, J.P. Gaudry, Z. Johnson, A.K., B. Mulloy, C. Powers, A. Jansma, A.E.I. Proudfoot, and T.M. Handel (2010) Characterization of the chemokine CXCL11 – heparin interaction suggests two different affinities for glycosaminoglycans. J BIOL CHEM. 285:17713-24.

Guttman M, Prieto JH, Handel TM, Domaille PJ, Komives EA. (2010) Structure of the Minimal Interface Between ApoE and LRP. J Mol Biol. 398:306-19.

A. Jansma, J. Kirkpatrick, A. Hsu, T.M. Handel and D. Nietlispach. (2010) NMR Analysis of the Structure, Dynamics and Unusual Oligomerization Properties of the Chemokine CTACK/CCL27. J BIOL CHEM. 285:14424-37.

Hanes MS, Jude KM, Berger JM, Bonomo RA, Handel T.M. (2009) Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. Biochemistry. 2009 48:9185-93.

D. Hamel & T.M. Handel. (2009) Editors: METHODS OF ENZYMOLOGY. Volumes 460 & 461 on Chemokines. Methods to probe the physical characteristics, dynamics, modifications, and interactions of chemokines and chemokine receptors. Preface.

D.J. Hamel, I. Sielaff, A.E.I. Proudfoot and T.M. Handel. (2009) Chapter 4. Interactions of Chemokines with Glycosaminglycans. METHODS OF ENZYMOLOGY 461:71-102.

A. Jansma, T.M. Handel and D. Hamel (2009) Chapter 2. Homo- and hetero-oligomerization of chemokines. METHODS OF ENZYMOLOGY 461:31-50. Handel is Corresponding Author.

M.O’Hayre, C.L. Salanga, P.C. Dorrestein and T.M. Handel. (2009) Phosphoproteomic Analysis of Chemokine Signaling Networks. METHODS OF ENZYMOLOGY. 460:331-46.

S.J. Allen, S. Ribeiro, R. Horuk, T.M. Handel (2009) Expression, Purification and In Vitro Functional Reconstitution of the Chemokine Receptor CCR1. PROTEIN EXPRESSION AND PURIFICATION. 66:73-81. PMCID: PMC2706832.

Winter JM, Jansma AL, Handel T.M., Moore BS. (2009) Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone. Angew Chem Int Ed Engl. 48:767-70.

CL Salanga, M. O'Hayre, and T.M. Handel. (2008) Modulation of Chemokine Receptor Activity Through Dimerization and Crosstalk. CELL MOL LIFE SCI. 66:1370-86. NIHMSID:130791.

X.Y. Du XY, B.A. Zabel, T. Myles, S.J. Allen, T.M. Handel, P.P Lee, E.C. Butcher, L.L. Leung. (2009) Regulation of Chemerin Bioactivity by Plasma Carboxypeptidase N, Carboxypeptidase B (TAFIa) and Platelets. J BIOL CHEM. 284:751-8. PMCID:2613638

B.A. Zabel, S. Nakae, L. Zuniga1, JY Kim, T. Ohyama, C. Alt, J. Pan, H. Suto, D. Soler, S. J. Allen, T.M. Handel, C. H. Song, S.J. Galli, E.C. Butcher. (2008) Mast Cell-Expressed Orphan Receptor CCRL2 Binds Chemerin and is Required for Optimal Induction of IgE-Mediated Passive Cutaneous Anaphylaxis. J EXP MED. 205:2207-20. PMCID:2556791

K.A. Reynolds, M.S. Hanes, J.M. Thomson, A.J. Antczak, J.M. Berger, R.A. Bonomo, J.F. Kirsch, and T.M. Handel (2008) Computational Redesign of the SHV-1 -lactamase/-lactamase Inhibitor Protein Interface. J MOL BIOL. 382:1265-75.

T.M. Handel, Z. Johnson, M. Mack, R. Cirillo, V. Muzio, M. Teixiera, M. Déruaz, F. Borlat, T.N.C. Wells, and A.E.I. Proudfoot (2008) An Engineered Monomer of CCL2 has Anti-inflammatory Properties Emphasizing the Importance of Oligomerization for Chemokine Activity In Vivo. J LEUKOCYTE BIOLOGY. 84(4):1101-8. PMCID: PMC2538597

S. Shahrara, AE.I. Proudfoot, C.C. Park, M.V. Volin, G.K. Haines, J.M. Woods, C.H. Aikens, T.M. Handel, R.M. Pope. (2008) Inhibition of MCP-1 Ameliorates Rat Adjuvant Induced Arthritis. J IMMUNOL 180: 3447-3456.

X. Zhang, Xiyun; J, DeChancie, H. Gunaydin, A. Chowdry, F. Clemente, A. Smith S. T.M. Handel, and K. Houk, (2008) Quantum mechanical design of enzyme active sites. J ORG CHEM 73:889-99.

M. O'Hayre, C.L. Salanga, T.M. Handel and S.J. Allens (2008) Chemokines and Cancer: Migration, Intracellular Signaling, and Intercellular Communication in the Microenvironment. BIOCHEMICAL J. 409:635-49. Handel is Corresponding Author.

S.J. Allen, B. A. Zabel, J. Kirkpatrick, E.J. Butcher, D. Nietlispach, and T.M. Handel (2007). NMR Assignment of Human Chemerin, a Novel Chemoattractant. Biomol. NMR ASSIGNMENTS 1:171-173.

A.B. Chowdry, K. Reynolds, M. Hanes, M. Voorhies, N. Pokala, T.M. Handel. (2007) An Object-Oriented Library for Computational Protein Design. J. COMPUTATIONAL CHEM 28:2378-88.

Douglas AE, Corbett KD, Berger JM, McFadden G, Handel TM. Structure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2. Protein Sci. 2007 16:695-703.

Kulig P, Zabel BA, Dubin G, Allen SJ, Ohyama T, Potempa J, Handel TM, Butcher EC, Cichy J. (2007) Staphylococcus aureus-derived staphopain B, a potent cysteine protease activator of plasma chemerin.J Immunol. 178:3713-20.

Allen SJ, Crown SE, Handel TM. (2007) Chemokine: receptor structure, interactions, and antagonism. Annu Rev Immunol. 25:787-820.

B.A. Zabel, T. Ohyama, L. Zuniga, J.Y. Kim, B. Johnston, S.J. Allen, D.G. Guido, T.M. Handel, E.C. Butcher. Chemokine-like Receptor 1 expression by macrophages in vivo: Chemerin-responsiveness and opposing regulation by TGF-beta and TLR Ligands. J Expt Hemat. 34:1106-14.

Zabel BA, Zuniga L, Ohyama T, Allen SJ, Cichy J, Handel TM, Butcher EC. (2006) Chemoattractants, Extracellular Proteases, and the Integrated Host Defense Response. Exp Hematol. 34:1021-32.

K. A. Reynolds, J. M. Thomson, K.D. Corbett, C. R. Bethel, J.M. Berger, J.F. Kirsch, R.A. Bonomo, and T.M. Handel. (2006) Structural and computational characterization of the SHV-1 -lactamase/-lactamase inhibitor protein (BLIP) interface. J Biol Chem. 81:26745-53.

S.E. Crown, Y. Yu, M.D. Sweeney, S.E. Crown, J.A Leary and T.M. Handel. (2006) Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding. J Biol Chem. 81:25438-46.

B.A. Zabel, S.J. Allen, P. Kulig, J.A. Allen, J. Cichy, T.M. Handel, E.C. Butcher. (2005) Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades. J Biol Chem 280:34661-6.

Y. Yu, M.D. Sweeney, O.M. Saad, A. Hsu, S.E. Crown, T.M. Handel and J.A Leary. (2005) Chemokine-glycosaminoglycan binding: specificity for CCR2 ligand binding to highly sulfated oligosaccharides using FTICR mass spectrometry. J Biol Chem 280:32200-8.

Z. Johnson, A.E.I. Proudfoot and T.M. Handel. (2005) Interaction of Chemokines and Glycosaminoglycans: A New Twist in the Regulation of Chemokine Function with Opportunities for Therapeutic Intervention. Cytokine Growth Factor Rev 16:625-36.

T.M. Handel, Z. Johnson, S.E. Crown, M. Sweeney, A.E. Proudfoot. (2005). Regulation of Chemokine Function by Glycosaminoglycans - As Exemplified by Chemokines. Annu Rev Biochem 74:385-410.

D. Huang, J. Wujek, G. Kidd, T. He, A. Cardona, M. Sasse, E. Stein, J. Kish, M. Tani, A.E. Proudfoot, B.J. Rollins, T.M. Handel, R.M. Ransohoff. (2005) Chronic Expression of Monocyte Chemoattractant Protein-1 in the Central Nervous System Causes Delayed Encephalopathy and Impaired Migroglial Function in Mice. The Faseb Journal, 19:761-72.

N. Pokala and T.M. Handel. (2005) Energy Functions for Protein Design II: Adjustment with Protein Complex Affinities, Reference States, and Properties of Designed Sequences. J Mol Biol 347:203-27.

R. Sandhoff, H. Grieshaber; R. Djafarzadeh, T.P. Sijmonsma, A.E.I. Proudfoot, T.M. Handel, H. Wiegandt, H. Wiegandt, P.J. Nelson. (2005) Chemokines Bind to Sulfatides as Revealed by Surface Plasmon Resonance. Biochim Biophys Acta, 1687:52-63.

E.K. Lau, A. Hsu, S. Allens and T.M. Handel (2004). Chemokine-Receptor Interactions: GPCRs, Glycosaminoglycans and Viral Chemokine Binding Proteins. Adv Protein Chem 68:351-91.

E.K. Lau, A. Kungl, C. Paavola, Z. Johnson, F. Borlat, A.E.I. Proudfoot, T.M. Handel. (2004) Identificationof the Glycosaminoglycan Binding Site of the CC Chemokine, MCP-1; Implications for Structure and Function In Vivo. J. OF BIOLOGICAL CHEMISTRY, 279:22294-305.

N. Pokala and T.M. Handel. (2004) Energy Functions for Protein Design I: Efficient and Accurate Continuum Electrostatics and Solvation. PROTEIN SCIENCE, 13:925-36.

T.M. Handel and E.K. Lau. (2003) Chemokine Structure and Receptor Interactions. Ernst Shering Research Foundation Workshop Series (45) on Chemokine Roles in Immunoregulation and Disease. 101-124.

B.T. Seet, C.A. McCaughan, T.M. Handel, G. McFadden and S. B. Fleming. (2003) Analysis of An Orf Virus Chemokine-Binding Protein: Shifting Ligand Specificities Among a Family of Poxvirus Viroceptors. PNAS, 100:15137-42.

L.A. Hardy, T.A. Booth, E.K. Lau, S. Ali, T.M. Handel and J.A. Kirby. (2004) Examination of MCP-1 (CCL2) Partitioning and Presentation During Transendothelial Leukocyte Migration. Lab Invest. 84:81-90.

A.E.I. Proudfoot, T.M. Handel, Z. Johnson, E.K. Lau, P. Liwang, I. Clark-Lewis, F. Borlat, T.N.C. Wells and M. Kosco-Vilbois. (2003) Glycosaminoglycan Binding and Oligomerization are Essential for the In Vivo Activity of Certain Chemokines. PNAS, 100:1885-1890. *EQUAL CONTRIBUTORS

J.M. Alexander, C.A. Nelson, V. van Berkel Fezzie, E.K. Lau, J.M. Studts, T.J. Brett, S.H. Speck, T.M. Handel, H.W. Virgin and D.H. Fremont. (2002) Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor. CELL, 111:343-56.

N. Pokala and T.M. Handel (2001) Review: Protein Design: Where We Were, Where We Are, Where We're Going. JOURNAL OF STRUCTURAL BIOLOGY, 134:269-281.

J.C. Lougheed, P.J. Domaille and T.M. Handel. (2002) Solution Structure and Dynamics of the Melanoma Inhibitory Activity Protein (MIA). JOURNAL OF BIOMOLECULAR NMR, 22:211-23.

B.T. Seet, R. Singh, C. Paavola, E.K. Lau, T.M. Handel and G. McFadden. (2001) Molecular Determinants for CC Chemokine Recognition by a Poxvirus CC-Chemokine Inhibitor. PNAS, 98:9008-13.

L.S. Mizoue, S.K. Sullivan, D.S. King, T.N. Kledal, T.N. Kledal, K.B. Bacon, T.M. Handel. (2001) Molecular Determinants of Receptor Binding and Signaling by CX3C Chemokine Fractalkine. J. OF BIOLOGICAL CHEMISTRY, 276: 33906-14.

J.C. Lougheed, J.M. Holton, T. Alber, J.F. Bazan, and T.M. Handel. (2001) Structure Of Melanoma Inhibitory Activity Protein (MIA), A Member of a recent identified family of Secreted Proteins. PNAS: 98:5515-5520.

L.A. Marcaurelle, J. Wilken, L.S. Mizoue, L. Oldham, T.M. Handel and C.R. Bertozzi. (2001) Chemical Synthesis of Lymphotactin, a GlycosylatedChemokine with a C-Terminal Mucin-like Domain. CHEMISTRY: A EUROPEAN JOURNAL 7:1129-1132.

T.M. Handel, Carolyn Bertozzi, and Jeff Hubbell. (2001) Biopolymer Engineering and Design: Beyond the Genome. CURRENT OPINION IN CHEMICAL BIOLOGY, 5:675-676.

D.A. Hoover, L. Mizoue, T.M. Handel and J. Lubkowski. (2000) The Crystal Structure Of The Chemokine Domain Of Fractalkine Shows A Novel Quaternary Arrangement. J. OF BIOLOGICAL CHEMISTRY 275:23187-23193.

G.A. Lazar, E.C. Johnson, J.R. Desjarlais and T.M. Handel. (1999) Rotamer Strain as a Determinant of Protein Specificity. PROTEIN SCIENCE. 8:2598-2610.

A.K. Chamberlain, K.M. Fisher, D. Reardon, T.M. Handel and S. Marqusee. (1999) Folding of an Isolated Ribonuclease H Core Fragment. PROTEIN SCIENCE.8:2251-2257.

K. Jarnagin, D. Grunberger, M. Mulkins, B.Wong, S. Hemmerich, C. Paavola, A.Bloom, S. Bhakta, R. Freedman, D. McCarley, I. Polsky, A. Ping-Tsou, A. Kosaka, T.M. Handel. (1999) Identification of Surface Residues of the Monocyte Chemotactic Protein-1 that Affect Signaling through the MCP-1 Receptor, CCR2b. BIOCHEMISTRY 38:16167-16177.

S. Hemmerich, C. Paavola, A. Bloom, S. Bhakta, R. Freedman, D. Grunberger, J. Krstenansky, S. Lee, D. McCarley, M. Mulkins, B. Wong, J. Pease, L. Mizoue, I. Polsky, K. Thompson, T.M. Handel, K. Jarnagin. (1999) Identification of Residues in the Monocyte Chemotactic Protein-1 that Contact the MCP-1 Receptor, CCR2b. BIOCHEMISTRY 38:13013-13025.

E.C. Johnson, G.A. Lazar, J.R. Desjarlais and T.M. Handel. (1999) Solution Structure and Dynamics of a Designed Hydrophobic Core Variant of Ubiquitin. STRUCTURE WITH FOLDING & DESIGN 7:967-76.

E.C. Johnson and T.M. Handel. (1999) The Effect of Hydrophobic Core Packing on Side Chain Dynamics. J. BIOMOLECULAR NMR. 15:135-143.

J.R. Desjarlais and T.M. Handel. (1999) Side-Chain and Backbone Flexibility in Core Design. J. MOLECULAR BIOLOGY 289:3 05-318.

Kirsch, J. F., Apicella, C. and Handel T. (1999) The Putative Low Barrier Hydrogen Bond in Pyridoxal Phosphate Dependent Enzymes. In "Enzymatic Mechanisms" Steenbock Symposium. IOS Press, Amsterdam. pp.198-203.

L. Mizoue, J.F. Bazan, E.C. Johnson and T.M. Handel. (1999) Solution Structure and Dynamics of the CX3C Chemokine Domain of Fractalkine and its Interaction with an N-terminal Fragment of CX3CR1. BIOCHEMISTRY 38:1402-1414.

G.A. Lazar and T.M. Handel. (1998) Hydrophobic Core Packing and Protein Design. CURRENT OPINION IN CHEMICAL BIOLOGY 2:675-679.

C. Paavola, S. Hemmerich, D. Grunberger, I. Polsky, A. Bloom, R. Freedman, M. Mulkins, S. Bhakta, D. McCarley, L. Wiesent, B. Wong, K. Jarnagin, T.M. Handel. (1998) Monomeric Monocyte Chemoattractant Protein-1 (MCP-1) Binds and Activates the MCP-1 Receptor CCR2b. J. OF BIOLOGICAL CHEMISTRY 273:33157-33165.

G. Kern, T.M. Handel and S. Marqusee. (1998) Characterization of a Folding Intermediate from HIV-1 RNase H. PROTEIN SCIENCE 7:2164-2174.

J.W. Bryson, J.R. Desjarlais, T.M. Handel and W.F. DeGrado. (1998) From Coiled Coils To Small Globular Proteins: Design of a Native-Like Three-Helix Bundle. PROTEIN SCIENCE, 7:1404-1414.

J. Davis, D. Agard, T.M. Handel and V. Basus. (1997) Alterations in Chemical Shifts and Exchange Broadening Upon Peptide Boronic Acid Inhibitor Binding to -lytic Protease. J. BIOMOLECULAR NMR 10:21-27.

J. Hedrick, V. Saylor, D. Figueroa, L. Mizoue, Y. Xu, S. Menon, J. Abrams, T.M. Handel, and A. Zlotnick. (1997) Lymphotactin is Produced by NK Cells and Attracts both NK and T Cells in vitro. J. OF IMMUNOLOGY. 158:1533-1540.

G. Lazar, JR Desjarlais, T.M. Handel. (1997) De Novo Design of the Hydrophobic Core of Ubiquitin. PROTEIN SCIENCE 6:1167-1178.

R. Fairman, R. Steed and T.M. Handel. (1997) Heteronuclear (1H, 13C, 15N) NMR Assignments and Secondary Structure of the Basic Region-Helix-Loop-Helix Domain of E47. PROTEIN SCIENCE 6:175-85.

J. Lubkowski, G. Bujacz, L. Boque, P.J. Domaille, T.M. Handel and A. Wlodawer. (1997) Structure of MCP-1 in Two Crystal Forms: A Rare Example of Variable Quaternary Interactions. NATURE STRUCTURAL BIOLOGY 4:64-9.

A.K. Chamberlain, T.M. Handel, and S. Marqusee. (1996) Detection of Rare Partially Folded Molecules in Equilibrium with the Native Conformation of RNASE H. NATURE STRUCTURAL BIOLOGY 3:782-7.

A.K. Chamberlain, T.M. Handel, and S. Marqusee. (1997) Detection of Protein Unfolding and Native State Fluctuations by Hydrogen Exchange. TECHNIQUES IN PROTEIN CHEMISTRY VIII. 727-734.

T.M. Handel and P.J. Domaille. (1996) Heteronuclear (1H, 13C, 15N) NMR Assignments and Solution Structure of the Monocyte Chemotactic Protein-1 (MCP-1) Dimer. BIOCHEMISTRY 35:6569-6584.

J.R. Desjarlais and T.M. Handel. De novo Design of the Hydrophobic Cores of Proteins. (1995) PROTEIN SCIENCE 4:2006-2018.

J.R. Desjarlais and T.M. Handel. (1995) New Strategies in Protein Design. CURRENT OPINIONS IN BIOTECHNOLOGY 6:460-466.

T.M. Handel, S.A. Williams, and W.F. DeGrado (1993) Metal-Ion Dependent Modulation of the Dynamics of a Designed Protein. SCIENCE 261:879-885.

T.M. Handel, and W.F. DeGrado (1993) Introduction of a Trp Resdiue into 4 as a Probe of Dynamics. J. AMER. CHEM. SOC. 115:4457-4460.

R. Hoess, U. Brinkmann, T.M. Handel and I. Pastian. (1993) Identification of a Peptide which Binds to the Carbohydrate Specific Monoclonal Antibody B3. GENE. 128:43-49.

J. Osterhout, T.M. Handel, A. Toumadje,W.C. Johnson, W.C. J. Hoch, D. Live, and W.F. DeGrado. (1992) Characterization of the Structural Properties of Alpha-1, a Peptide Designed to Form a 4-Helix Bundle. J. AMER. CHEM. SOC. 114:331-337.

T.M. Handel. Protein Design In: "First Forsight Conference on Nanotechnology" (Crandall, B.C. and Lewis,J., Eds.) MIT Press, 1992, pg 37-45.

T.M. Handel and W.F. DeGrado (1990) De Novo Design of Zn+2-Binding Proteins. J. AMER. CHEM, SOC. 112:6710-6711.

T.M. Handel. (1990) De Novo Design of an Barrel Protein. PROTEIN ENGINEERING 3:233-234.

F.H. Roerdink, J. Regts, T.M. Handel, S.M. Sullivan, J.D. Baldeschwieler and G.L. Scherphof. (1989) Effect of Cholesterol on the Uptake and Intracellular Degradation of Liposomes by Liver and Spleen: A Combined Biochemical and -ray Perturbed Angular Correlation Study. BIOCHIMICA ET BIOPHYSICA ACTA 980:234-240.

R.P. Goodrich, T.M. Handel and J.D. Baldeschwieler. (1988) Modification of Lipid Phase Behavior with Membrane-Bound Cryoprotectants. BIOCHIMICA ET BIOPHYSICA ACTA 938:143-54.

T.M. Handel, I.S. Ponticello and J.S. Tan. (1987) Effects of Side-Chain Structure on Polymer Conformation: Synthesis and Dilute Solution Properties. MACROMOLECULES 20:264-7.

J.S. Tan and T.M. Handel. (1985) Cooperative Interactions of Anionic Dyes with Imidazole-Containing Polymers. MICRODOMAINS IN POLYMER SOLUTIONS 417-427.

J.N. Cooper, J.G. Bentsen, T.M. Handel, K.M. Strohmaier, W.A. Porter, B.C. Johnson, A.M. Carr, D.A. Farnath and S.L. Appleton. (1983) Trans-[(en)2Co(Cl)(S2O3)], Na[trans-[(en)2Co(C2O4)(S2O3)]], trans-[(en2Co(NCO)(S203)], and the Nature of [(en)2Co(OH2)(S2O3)]+ in Aqeous Solution. INORGANIC CHEM. 22:3060-3065.

J.S. Tan and T.M. Handel. (1982) Cooperative Interactions of Anionic Dyes with Imidazole-Containing Polymers. POLYMER PREPRINTS. 23:48-49.

J.S. Tan and T.M. Handel. (1982) Interaction of Polymers with Dyes and Ions. Proc IUPAC, I.U.P.A.C. MACROMOLECULAR SYMPOSIUM, 28th, 885.