University of California, San Diego | Skaggs School of Pharmacy and Pharmaceutical Sciences


Dr. Vivian Hook

Principal Investigator

Mailing Address:
9500 Gilman Drive #0744
La Jolla, CA 92093-0744

Telephone: 858-822-6682
Fax: 858-822-6681

Jill Wegrzyn


Mailing Address:
9500 Gilman Drive #0744
La Jolla, CA 92093-0744

Telephone: 858-822-6695
Fax: 858-822-6696


Shin-Rong Hwang Molecular Biology/Biochem 822-6684
Steven Bark Mass Spectrometry/Proteomics 822-6685
Lydiane Funkelstein Neurobiology 822-6684
Doug Lu Biophysics/Biochem 822-6685
Thomas Toneff Neurochemistry 822-6684
Jill Wegrzyn Bioinformatics 822-6695
Charles Mosier Neurochemistry 822-6684
Ardalan Minokadeh Neurosciences 822-6685
Gloria Sanchez School of Pharmacy 822-6684
Graduate Student Research Rotations - Summer Research Internships
Undergraduate Research, Independent Study
Visiting Students and Scientists

Publications In Press:

Hook, V., Funkelstein, L., Lu, D., Bark, S., Wegrzyn, J., and Hwang, S.-R. (2007) Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu. Rev. Pharmacol. Tox.

Bark, S.J., and Hook, V. (2007) Differentical recovery of peptides from sample tubes and the reproducibility of quantitative proteomic data. J. Proteome Research.


Hook, G., Hook, V.Y.H., and Kindy, M. (2007) Cysteine protease inhibitors reduce brain beta-amyloid and beta-secrease activity in vivo and are potential Alzheimer's disease therapeutics. Biol. Chem. 388, 979-983.

Hwang, S.R., and Hook, V.Y.H. (2007) Multiple domains of endopin 2A for serpin cross-class inhibition of papain. Arch. Biochem. Biophys. 46, 219-224.