Dr. April Lukowski, Ph.D.

Assistant Professor
Skaggs School of Pharmacy and Pharmaceutical Sciences
Scripps Institution of Oceanography


April Lukowski, Ph.D.
(858) 534-3907


Teah Stacks

Human Resources

Lydia Heidt (formerly Napa)

Fund Management

Lisa Jandt Auvil

Research Summary

Research in the Lukowski lab aims to understand and harness the unique chemistry of marine life through the discovery of novel biosynthetic enzymes and exploring their biocatalytic potential in an inclusive, collaborative, and multidisciplinary environment. We use techniques in enzymology, chemical analysis, and bioinformatics to identify and characterize new biocatalysts and enzyme families for their substrate scopes and reactivities with a goal of generating new natural product-derived therapeutics.

Academic Achievements

Education: B.S. in Biochemistry (2015) Saginaw Valley State University; Ph.D. in Chemical Biology (2020) University of Michigan; Postdoctoral studies (2020-2023) Scripps Institution of Oceanography.

Awards and Honors: NIH NRSA Postdoctoral Fellowship (2021), NIH NRSA Predoctoral Fellowship (2019), Rackham Predoctoral Fellowship (2019), American Chemical Society Outstanding Graduate in Chemistry (2015).

Key Contributions
  • Discovered and characterized a new family of flavin-dependent halogenases capable of halogenating alkynes.
  • Elucidated biosynthetic pathways for marine toxins impacting human and animal health.
Selected Publications

Selected Publications – view more

denotes corresponding author

*denotes co-first author

Potential Collaborative Programs
  • Expertise in enzyme expression, purification, activity assessment, and biocatalytic application
  • Experience in a broad scope of techniques in biosynthetic pathway elucidation, including synthetic biology, chemical isolation and analysis, and in vitro reactions.