Professor Sepassi headshot

Dr. Aryana Sepassi, Pharm D, MAS

Assistant Professor of Clinical Pharmacy
Skaggs School of Pharmacy and Pharmaceutical Sciences 

Aryana Sepassi, PharmD, MAS
Email
a1sepassi@health.ucsd
Phone
(669) 248-9909
Research Summary

Professor Sepassi is a pharmacist, health economist, and outcomes scientist. Her research mission is to improve healthcare accessibility for immigrants in the United States by generating empiric data that accomplishes three main goals:

  1. To identify socioeconomic disparities and their contributions among immigrants and other disadvantaged populations that prevent access to high-quality healthcare.
  2. To quantify the harmful health effects of discriminatory health policies toward these populations.
  3. To aid in the development of cost-effective interventions to bridge gaps and improve care.

Professor Sepassi's research focuses on the use of econometric, epidemiologic, data science, and causal inference methods to carry out quasi-experimental projects. She has experience with the Medical Expenditure Panel Survey, California Health Interview Survey, insurance claims data from IQVIA (formerly Quintiles IMS), Medicare claims data, linked SEER-Medicare data, Healthcare Cost and Utilization Project data, and EMR data specific to the UC system.

Professor Sepassi has mentored several students who have gone on to accept fellowship and industry positions, and her work on health literacy and immigrant populations in the United States has been cited by Migration Policy Institute. Her work has been funded by the American Cancer Society, and the Arthritis Foundation. She is the recipient of a 2024 Loan Repayment Program Award from the National Cancer Institute for work on access to targeted oral anticancer medications among self-identified racial/ethnic minority populations in the United States.

Academic Achievements

Education: B.S in Neuroscience and Physiology, University of California, San Diego (2012); Pharm.D., University of California, San Diego Skaggs School of Pharmacy & Pharmaceutical Sciences (2016); Post-Doctoral Fellowship, Health Economics & Outcomes Research, University of California, San Diego (2018); Master of Advanced Studies (MAS) in Clinical Research (2023), University of California San Diego.

Awards and Honors:  Loan Repayment Program Awardee, National Cancer Institute (2024).

Leadership Experience:  Dr. Sepassi is an active member of the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) and the Society for Medical Decision Making (SMDM). She is currently on the leadership committee for SMDM’s Special Interest Group in Open-Source Health Economic Modelling. She is also an Assistant Editor for the Journal of Pharmaceutical Health Services Research (JPHSR) and is a peer-review board member for Health Affairs Scholar (HAS).

Teaching

Co-Chair, Applied Pharmacoeconomics (SPPS 209)

  • Evaluation of predicted health literacy rates in self-identified racial/ethnic immigrant minorities (cited by Migration Policy Institute), and COVID-19 vaccine acceptance rates in overall immigrant populations
  • Evaluation of disparities in the colorectal cancer care continuum among rural-living individuals
  • First evaluation of Metformin-induced Vitamin B12 deficiency among people with Type 2 Diabetes using a large, real-world national database (All of Us)

 

Selected Publications
  • Sepassi A, Garcia S, Tanjasiri S, Lee S, Bounthavong M. (2023). Predicted health literacy disparities between immigrant and US-born racial/ethnic minorities: a nationwide study. JGIM. 38(10): 2364-2373.
  • Sepassi A, Li M, Zell JA, et al. (2024). Rural-urban disparities in colorectal cancer screening, diagnosis, treatment, and survivorship care: a systematic review and meta-analysis. The Oncologist. 29(4):e431-e446.
  • Sepassi A, Saunders IM, Bounthavong M, et al. (2023). Cost effectiveness of letermovir for cytomegalovirus prophylaxis compared with pre-emptive therapy in allogeneic hematopoietic stem cell transplant recipients in the United States. PharmacoEconomics Open. 7(3):393-404.
  • Sepassi A, Li M, Suh K, Stottlemyer B, Bounthavong M. (2024). Association of Opioid and Concurrent Benzodiazepine, Skeletal Muscle Relaxant, and Gabapentinoid Usage on Healthcare Expenditure and Resource Utilization: A Serial Cross-Sectional Study, 2009 to 2019. Substance Use and Addiction Journal. 45(4):631-644.
Potential Collaborative Programs

 

  • Evaluation of health policy effects on prescription medication out-of-pocket spending in disadvantaged populations (e.g. Inflation Reduction Act)
  • Cost-effectiveness modelling
  • Evaluation of the effects of social determinants of health (e.g. socioeconomic status) and socio-cultural structures on healthcare attitudes and utilization among immigrant populations.