Dr. Jair Lage de Siqueira-Neto

Drug Discovery, High- Throughput, High-Content Screening

Jair Lage Photo
Jair Lage de Siqueira-Neto, Ph.D.

Associate Adjunct Professor
Skaggs School of Pharmacy and Pharmaceutical Sciences

(858) 822-5595
Research Summary

Dr. Siqueira-Neto’s research has focused on molecules and natural products against human diseases, especially infectious diseases and cancers.

Academic Achievements


B.S. in Biological Sciences (2003) University of Campinas, SP - Brazil; Ph.D. in Molecular Genetics (2007) University of Campinas, SP - Brazil; Postdoctoral Fellow (2007-2009) Institut Pasteur Korea - South Korea.

Awards and Honors:

Outstanding Mentor of 2017 – UC San Diego Faculty Mentorship Program Award (2017); National Center of Leadership in Academic Medicine Award (2016); Finalist of the Brazilian Diaspora Network Award in Health Sciences (2015); Sage Scholar (2015); GSK Fastrack Competition (2013); DNDi Project of the year (2010); CAPES International Scientific Interchange Program Fellowship – Korea (2006); CAPES Doctor of Philosophy Fellowship (2003-2007); Brazilian Corporation of Agricultural Research (Embrapa) Fellowship (2001-2003); FAPESP Fellowship for Scientific Initiation (2000-2001)

Leadership Experience:

Team Leader and Drug Discovery Program Coordinator at Institut Pasteur Korea (2009-2012); Kinetoplastida Core Director from the Center for Discovery and Innovation in Parasitic Diseases, UCSF & UCSD (2013-present); Assistant Adjunct Professor at Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego (2014-present), UC San Diego Screening Core Director (2017-present).

Key Contributions
  • Advanced the field of drug discovery and development against Chagas disease, identifying new chemical structures, some of which have advanced to clinical candidates
  • Identified new active molecules against Leishmania parasites
  • Advanced the field of drug discovery and development against viruses, including Zika virus
  • Contributed in the field of new therapies for glioblastoma
  • Molecular targets of interest include protease inhibitors and RNA polymerase inhibitors
  • Contributed with methods to identify molecular targets of novel active compounds and study the therapeutic mechanism of action.
Selected Publications
Potential Collaborative Programs
  • Drug discovery for neglected tropical diseases
  • High-Throughput, High-Content Screening assay development